Pyridines and derivatives
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- (1)
- (5)
- (5)
- (520)
- (22)
- (2,105)
- (22)
- (2)
- (5)
- (5)
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- (175)
- (1)
- (14)
- (50)
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- (86)
- (225)
- (6)
- (4)
- (2)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (5)
- (1)
- (12)
- (4)
- (8)
- (7)
- (12)
- (60)
- (867)
- (5)
- (55)
- (60)
- (58)
- (19)
- (346)
- (2)
- (4)
- (2)
- (1)
- (1)
- (5)
- (275)
- (1)
- (1,700)
- (2)
- (27)
- (7)
- (1)
- (92)
- (4)
- (13)
- (77)
- (128)
- (54)
- (59)
- (2)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (1)
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- (1)
- (1)
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- (1)
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- (2)
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- (1)
- (1)
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- (1)
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- (9)
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- (1)
- (2)
- (4)
- (2)
- (1)
- (5)
- (17)
- (23)
- (1)
- (1)
- (60)
- (21)
- (1)
- (1)
- (29)
- (49)
- (7)
- (2)
- (1)
- (5)
- (6)
- (12)
- (1)
- (1)
- (1)
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- (1)
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- (1)
- (11)
- (5)
- (1)
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- (1)
- (1)
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- (7)
- (1)
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- (1)
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- (2)
- (1)
- (1)
- (1)
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- (1)
- (1)
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- (15)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (12)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (2)
- (1)
- (15)
- (17)
- (4)
- (2)
- (2)
- (5)
- (2)
- (3)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (7)
- (5)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (16)
- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
- (2)
- (9)
- (3)
- (2)
- (1)
- (1)
- (3)
- (6)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (1)
- (3)
- (3)
- (1)
- (6)
- (5)
- (2)
- (1)
- (19)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (22)
- (22)
- (2)
- (2)
- (1)
- (1)
- (2)
- (2)
- (22)
- (16)
- (6)
- (2)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (12)
- (48)
- (1)
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- (2)
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- (1)
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- (1)
- (1)
- (7)
- (9)
- (22)
- (30)
- (1)
- (1)
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- (11)
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- (1)
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- (55)
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- (4)
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- (1)
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- (26)
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- (1)
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![Medchemexpress LLC Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | 2361742-30-3 | 99.9% | C16H8ClF3N4O | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC Benzoic acid, 3-chloro-4-cyano-, 2-[4-cyano-2-(trifluoromethyl)phenyl]hydrazide | 2361742-30-3 | 99.9% | C16H8ClF3N4O | 1 ML
Small and Specialty Supplier Partner
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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VPC-70619 is a potent N-Myc inhibitor that blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box. It demonstrates potent inhibitory activity against N-Myc-dependent cell lines and can partially reverse paclitaxel resistance in cells by reducing MYCN expression. It is suitable for cancer research, including neuroblastoma and thyroid cancer.
- Potent N-Myc inhibitor
- Blocks binding of N-Myc-Max heterocomplex to DNA E-box
- Potent inhibitory activity against N-Myc-dependent cell lines
- Can partially reverse paclitaxel resistance by reducing MYCN expression
- Suitable for cancer research
- High stability in liver microsomes
- Upregulates MYCN, MDM2, and CRABP2 mRNA levels
- Downregulates TGM2 and INHBA
- Inhibits proliferation, migration, and aggressiveness of SW1736-PTX and 8505C-PTX cells
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Gsk2656157 | 1337532-29-2 | 416.45 | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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GSK2656157 is a selective and ATP-competitive inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) with an IC50 of 0.9 nM. It inhibits PERK activation and decreases downstream substrates such as phospho-eIF2α, ATF4, and CHOP.
- Blocks de novo protein synthesis after UPR induction
- Inhibits the growth of HT1080 cells
- Reduces LPS-induced IL-1β production, Caspase 1 activation, and eIF-2α phosphorylation
- Demonstrates dose-dependent inhibition of phospho-PERK Thr980 in vivo
- Inhibits tumor growth in human tumor xenograft models in vivo
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Apexbio Technology LLC GnRH Associated Peptide (GAP) (1-13), human 100111-07-7 10mg
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GnRH Associated Peptide (GAP) (1-13) human (CAS 100111-07-7) corresponds to the amino acid sequence Asp-Ala-Glu-Asn-Leu-Ile-Asp-Ser-Phe-Gln-Glu-Ile-Val derived from the N-terminal region of human GAP This peptide originates from the precursor of gonadotropin-releasing hormone (GnRH) which is co-released with GnRH from hypothalamic neurons into the pituitary portal system GAP (1-13) has been shown to suppress prolactin secretion and stimulate gonadotropin release implicating a modulatory role in neuroendocrine pathways governing reproductive and pituitary function The peptide is utilized in research on hypothalamic-pituitary axis regulation neuroendocrine signaling and mechanisms controlling hormone secretion
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Apexbio Technology LLC Dynorphin (2-17), amide, porcine 10mg
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Dynorphin 2-17 amide porcine is an endogenous opioid peptide derived from the proteolytic cleavage of the prodynorphin precursor predominantly processed by proprotein convertase 2 (PC2) in synaptic terminals It modulates nociceptive responses by influencing opioid and bradykinin receptor pathways in the central nervous system including the hypothalamus hippocampus striatum and spinal cord Dynorphin 2-17 amide porcine exerts its biological activity primarily through regulation of calcium influx via voltage-sensitive channels contributing to pain modulation processes Based on these pharmacological properties Dynorphin 2-17 amide porcine holds research potential in studies of pain perception neuropathic pain mechanisms and analgesic drug development
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Apexbio Technology LLC NE 100 hydrochloride 10mg
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NE 100 hydrochloride (CAS 149409-57-4) is a selective antagonist of the sigma-1 receptor exhibiting an IC50 value of 4 16 nM By targeting the sigma-1 receptor this small molecule has been shown to inhibit ER stress-induced hippocampal cell death and demonstrates antipsychotic activity in preclinical models NE 100 hydrochloride is widely utilized in basic neuroscience research to investigate the physiological and pathological roles of sigma-1 receptor signaling particularly in the context of neuropsychiatric disorders and neuroprotection
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eMolecules 4-AMINO-3 5-DICHLOROPYRI 250MG
5000191859 4-AMINO-3 5-DICHLOROPYRI 250MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000379132 PROTOAPIGENONE 1MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000442328 PHOSPHO-CHK2 THR68 50UL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000444098 PHOSPHO-PAXILLIN TY 100UL
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000445340 ARMENIAN HAMSTER ANT 100T
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Medchemexpress LLC Luspatercept 50mg | 50mg
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Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor superfamily ligands Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors Luspatercept binds with GDF11 and inhibits Smad2/3 signaling Luspatercept can be used for the research of anemia[1]
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Medchemexpress LLC Clindma | 908860-82-2 | MFCD00382831 | 99.9% | 808.35 | C54H97NO3 | 5 MG
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CLinDMA is a cationic lipid used in research to formulate lipid nanoparticles for nucleic acid delivery. It is supplied for research use only and has been reported to induce inflammatory responses; users should consult the batch COA and SDS for exact purity and handling instructions.
- Cationic lipid for lipid nanoparticle formulation.
- Applicable to siRNA and other nucleic acid delivery research.
- Reported high purity but supplier-dependent; verify with batch COA.
- Soluble in DMSO and offered as solid or ready-to-use solution (e.g., 10 mM in DMSO).
- Reported appearance: light yellow to yellow viscous liquid.
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Medchemexpress LLC CATHEPSIN B HUMAN 50UG
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5000194743 CATHEPSIN B HUMAN 50UG
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eMolecules 13862-28-7 | Potassium methyltrifluoroborate | Combi-Blocks | MFCD08276757 | 121.940 | CH3BF3K | 96.000 | [K+].C[B-](F)(F)F | 5g | 117575828
Potassium methyltrifluoroborate | Combi-Blocks | 13862-28-7 | MFCD08276757 | 121.940 | CH3BF3K | 96.000 | [K+].C[B-](F)(F)F | 5g | 117575828
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Medchemexpress LLC GelHP Protein Gel (Tris-Gly, 15%, 15 well) | 10 EA
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This GelHP protein gel is a precast polyacrylamide gel, offering a safe, convenient, and high-performance solution for protein separation. It is suitable for both PAGE and Western blot analysis, formulated without SDS for use in both denaturing and native electrophoresis.
- Coated plastic gel plates minimize non-specific protein adsorption for sharper bands.
- Easy-open cassette design for effortless gel plate removal.
- SDS-free formulation compatible with denaturing and native PAGE.
- Automated gel casting ensures high batch-to-batch stability and reproducibility.
- Compatible with most mainstream mini gel electrophoresis systems.
- Available in multiple uniform and gradient concentrations.
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